Jonathan Sexton returns to the Leinster squad as Leo Cullen makes six changes for to his side as they host the Ospreys tomorrow night.
Sexton makes his first appearance for the province since undergoing shoulder surgery which ruled him out of Ireland's tour of South Africa in June.
Zane Kirchner continues in the number 15 jersey with Isa Nacewa captaining the side once again from the right wing and Dave Kearney selected on the left.
Noel Reid and Garry Ringrose continue in the centre.
Luke McGrath starts at scrum half while Sexton makes his first appearance of the campaign from number ten.
In the pack there are two changes in the front row with Cian Healy and Tadhg Furlong coming in, with Sean Cronin continuing at hooker.
Mick Kearney comes in to the second row having lined out for Clontarf in the All-Ireland League last weekend to partner Devin Toner.
There is one final change in the back row as Josh van der Flier starts at open side flanker with Jordi Muprhy and Jamie Heaslip completing the line up.
Rhys Ruddock makes his first match day squad of the season having returned from injury and he is named on the bench.
Leinster XV to face Ospreys - Caps in brackets
15. Zane Kirchner (68)
14. Isa Nacewa (C) (150)
13. Garry Ringrose (25)
12. Noel Reid (62)
11. Dave Kearney (105)
10. Johnny Sexton (126)
9. Luke McGrath (53)
1. Cian Healy (156)
2. Sean Cronin (115)
3. Tadhg Furlong (53)
4. Devin Toner (182)
5. Mick Kearney (10)
6. Jordi Murphy (83)
7. Josh van der Flier (27)
8. Jamie Heaslip (218)
Replacements
16. James Tracy (18)
17. Jack McGrath (96)
18. Mike Ross (137)
19. Ross Molony (26)
20. Rhys Ruddock (113)
21. Dan Leavy (16)
22. Jamison Gibson-Park (3)
23. Joey Carbery (4)
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