Louis van Gaal's first Champions League group match in charge of Manchester United has resulted in a 2-1 defeat to PSV.
United taken a 1-0 lead shortly before half-time thanks to a fine finish from ex-PSV winger Memphis Depay, minutes after club colleague Luke Shaw suffered a suspected broken leg in challenge with Hector Moreno.
However, Moreno headed in a corner and Luciano Narsingh's header from a pinpoint left-wing cross from Maxime Lestienne gave the Dutch champions the lead.
Meanwhile, Man City slipped up at home to last year's runners-up Juventus. Like United they took the lead, when Vincent Kompany headed in from close range.
But Juve fought back with a goal from Mario Mandzukic and an excellent finish from just outside the box from Alvaro Morata.
UEFA Champions League Results
Paris Saint-Germain 2-0 Malmo
Real Madrid 4-0 Shakhtar Donetsk
PSV 2-1 Man United
Wolfsburg 1-0 CSKA Moscow
Benfica 2-0 FC Astana
Galatasaray 0-2 Atletico Madrid
Man City 1-2 Juventus
Sevilla 3-0 Bor Monchengladbach
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