From the Manchester derby and Ireland's autumn series opener to the club Championships, it is an action-packed weekend of sport.
Of course, Off the Ball will have coverage of all the sport taking place across the weekend.
OTB Saturday, 1-5pm
1:30pm Half Time at the Aviva
Andy Dunne with updates from Ireland against Japan.
2pm Saturday Panel
3-5pm OTB Football Saturday
Mark Lawrenson, Dan McDonnell and Johnny Ward with all of the football talking points.
OTB Sunday, 1-7pm
11:30am-12:30pm Sunday Paper Review
Orla McElroy and Bernard Jackman join John Duggan to discuss Sunday's sports pages.
2pm Live Premier League commentary
Bernard O'Toole and Brian Kerr call Everton against Tottenham Hotspur.
4:30pm Live Premier League commentary
Joe Molloy and Keith Treacy call West Ham against Liverpool.
On top of all of the exclusive coverage of the sporting weekend on OTB Sports, there is a whole host of sport to watch, live across all TV stations.
Day 2 of WWT Championship from Mexico on Sky Sports Golf.
St Patrick’s Athletic play Sligo Rovers in the Premier Division from Richmond Park on RTÉ 2.
Leicester take on Bath in the Gallagher Premiership live on BT Sport 1.
Ronan O'Gara's La Rochelle face Bordeaux Begles in the French Top 14 on Premier Sports 2.
Southampton against Aston Villa in the Premier League on Sky Sports Main Event.
The Breeders’ Cup begins on ITV4.
Live coverage of the qualifying of the MotoGP Grand Prix of Algarve on BT Sport 2.
The Manchester derby, live on Sky Sports Main Event.
International rugby, as Ireland take on Japan in the Aviva Stadium on RTÉ 2. Italy host New Zealand on Amazon Prime.
Racing on TG4, live from Naas. Additionally, ITV4 have racing action from Wincanton, Doncaster and Aintree.
Toulouse against Perpignan in the French Top 14 on Premier Sports 2.
Chelsea take on Burnley in the Premier League, on Premier Sports 1.
More international rugby as England host Tonga in the Autumn Internationals on Amazon Prime.
Brive meet Racing 92 in the French Top 14 on Premier Sports 2.
Club Championships: Dublin senior football semi-final coverage is live on RTÉ 2, which sees St Judes taking on Lucan Sarsfields in the first game at 5.15pm, before Kilmacud Crokes play Ballyboden St-Enda’s at 7pm in the second match.
International rugby sees Wales against South Africa in the Autumn Internationals, live on Amazon Prime.
BT Sport 1 has Brighton up against Newcastle United in the Premier League.
Blackpool against QPR in the Championship on Sky Sports Main Event.
RB Leipzig take on Borussia Dortmund in the Bundesliga on Sky SportS Mix.
The third round of the WWT Championship on the PGA Tour on Sky Sports Golf.
Qualifying from the Mexico City Grand Prix is on Sky Sports F1.
WNL on TG4 sees DLR Waves play Peamount United.
France host Argentina in the Autumn Internationals on Amazon Prime.
Real Madrid face Rayo Vallecano in La Liga on Premier Sports 2.
Bordeaux take on Paris Saint-Germain in Ligue 1 on BT Sport 2.
Ian Garry will make his UFC debut in the UFC 268 card, the prelim card action starts on BT Sport 1.
Dundee take on Celtic in the Scottish Premiership on Sky Sports Main Event.
Marseille against FC Metz in Ligue 1 on BT Sport 3.
Tottenham face Manchester United in the FA Women’s Super League on BBC Two.
MotoGP Grand Prix of Algarve, on BT Sport 2.
Ballyhale Shamrocks meet O’Loughlin Gaels in the Kilkenny senior hurling final on TG4.
Arsenal take on Watford in the Premier League on Sky Sports Main Event.
International rugby sees Scotland play Australia on Amazon Prime
England host New Zealand on BBC Two.
Donegal senior football live on TG4 as Naomh Conaill play St Eunan’s.
Atletico Madrid against Valencia in La Liga on Premier Sports 1.
Wasps take on Harlequins in the Gallagher Premiership on BT Sport 1
Sky Sports Main Event has West Ham taking on Liverpool in the Premier League.
Cleveland Browns against the Cincinnati Bengals on Sky Sports NFL.
LOI TV has Bohemians against Drogheda United and Dundalk taking on Longford Town, while UCD take on Treaty United and Galway United host Bray Wanderers in the play-off semi-final second legs.
Formula 1 Mexico City Grand Prix is live on Sky Sports Main Event.
The final round of the WWT Championship on the PGA Tour, live on Sky Sports Golf.
The Milan derby is on BT Sport 1.
Clermont face Toulon in the French Top 14 on Premier Sports 1.
Green Bay Packers take on the Kansas City Chiefs on Sky Sports Main Event.