FIFA's Referees' Committee chairman Pierluigi Collina said that the football body is looking to implement VAR uniformly across all competitions as it takes over direct responsibility for the system.
Issues concerning VAR have been handled primarily by the game's law-making body, International Football Association Board (IFAB), during the system's two-year experimental phase, and its introduction as part of the laws of the game.
FIFA has sent a letter to national associations saying it has taken over all VAR related activities from the IFAB. It means Collina will now be in charge instead of David Elleray, the former English referee, IFAB’s technical director who had been seen as the chief architect of VAR.
Collina, the Italian former World Cup referee, will oversee VAR and has made it clear that he wants the system to be used the same way across the world, calling the move a "natural transition".
"IFAB as an organisation has the duty to govern the laws of football, including VAR and the protocol and regulations. Once the laws of the game are set, IFAB's job is over," he said.
"It is then FIFA that deals with referees' education around the world supporting all the member associations."
There have been some variations in the use of VAR in different competitions and national leagues, but Collina said there should be a uniform approach.
"Another responsibility of FIFA's is to have the laws of the game implemented all over the world in the same way, there cannot be different implementation of the laws of the game in different continents or different countries. Our responsibility is to ensure that football is played in the same way all over the world.
"Can you imagine in international competition played by teams who are used to having different interpretations of the laws of the game in their domestic competition?
"Saying that, VAR should be used in the same way all over the world is something obvious. Of course, there can be some small differences, but the general implementation should be the same.
"It is FIFA and IFAB's responsibility to have the game played the same way across the world, for the benefit of those who are playing," he said.
The Premier League has not used VAR to check for encroachment off the line by goalkeepers during penalty kicks despite that element being part of the protocol.
Speaking generally, Collina said FIFA wanted to avoid situations where players in an international tournament faced surprise decisions.
"If something is written in the laws of the game, it has to be implemented everywhere, otherwise can you imagine the surprise of someone who is penalised for something in an international game that he is not penalised for at home?
"Maybe they would not be aware of what they can do? If something in the laws of the game doesn’t work, then it is discussed and eventually changed by IFAB."